Direct Synthesis of Cyclodextrin-Rotaxanated Poly(ethylene glycol)s and Their Self-Diffusion Behavior in Dilute Solution
Poly[(ethylene glycol)-rotaxa-(α-cyclodextrin)]s, (PEG-rotaxa-αCD)s, were prepared by a direct route from commercially available poly(ethylene glycol)s (PEG) with molecular weights from 1.5 to 20 kg/mol. The rotaxanated structure was verified by diffusion-ordered 2D NMR spectroscopy (DOSY). The self...
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Veröffentlicht in: | Macromolecules 2003-12, Vol.36 (26), p.9859-9865 |
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Zusammenfassung: | Poly[(ethylene glycol)-rotaxa-(α-cyclodextrin)]s, (PEG-rotaxa-αCD)s, were prepared by a direct route from commercially available poly(ethylene glycol)s (PEG) with molecular weights from 1.5 to 20 kg/mol. The rotaxanated structure was verified by diffusion-ordered 2D NMR spectroscopy (DOSY). The self-diffusion coefficients for PEG-rotaxa-αCD and PEG in dilute DMSO-d 6 scale with their respective molecular weights as D PEG - rotaxa - αCD ∼ M n -0.60±0.05 and D PEG ∼ M n -0.55±0.03. With increasing temperature, the hydrodynamic radius of the PEG-rotaxa-αCD increases by the same slope as the unthreaded PEG backbone. These polyrotaxanes, in which up to 70% of the backbone is covered with cyclodextrins, behave as random coils in good solvents. |
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ISSN: | 0024-9297 1520-5835 |
DOI: | 10.1021/ma035513f |