Dipolar Cycloaddition of Ethyl Isocyanoacetate to 3-Chloro-2-(methylthio)/2-(methylsulfonyl)quinoxalines:  Highly Regio- and Chemoselective Synthesis of Substituted Imidazo[1,5-a]quinoxaline-3-carboxylates

Dipolar Cycloaddition of Ethyl Isocyanoacetate to 3-Chloro-2-(methylthio)/2-(methylsulfonyl)quinoxalines:  Highly Regio- and Chemoselective Synthesis of Substituted Imidazo[1,5-a]quinoxaline-3-carboxylates

An efficient route for regio- and chemoselective synthesis of substituted 3-(carboethoxy)imidazo[1,5-a]quinoxalines and novel diimidazo[1,5-a:5‘,1‘-c]quinoxalines via base-induced cycloaddition of ethyl isocyanoacetate to unsymmetrically substituted 3-chloro-2-(methylthio)/2-(methylsulfonyl)quinoxal...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of organic chemistry 2007-06, Vol.72 (13), p.5020-5023
Hauptverfasser: Sundaram, G. S. M, Singh, B, Venkatesh, C, Ila, H, Junjappa, H
Format: Artikel
Sprache:eng
Schlagworte:
Carboxylic Acids - chemical synthesis
Carboxylic Acids - chemistry
Chlorine - chemistry
Imidazoles - chemistry
Isocyanates - chemistry
Methylation
Molecular Structure
Quinoxalines - chemistry
Sulfhydryl Compounds - chemistry
Sulfur - chemistry
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:An efficient route for regio- and chemoselective synthesis of substituted 3-(carboethoxy)imidazo[1,5-a]quinoxalines and novel diimidazo[1,5-a:5‘,1‘-c]quinoxalines via base-induced cycloaddition of ethyl isocyanoacetate to unsymmetrically substituted 3-chloro-2-(methylthio)/2-(methylsulfonyl)quinoxalines has been reported.
ISSN:0022-3263
1520-6904
DOI:10.1021/jo070590k