(+)-1-(3S,4R)-[3-(4-Phenylbenzyl)-4- hydroxychroman-7-yl]cyclopentane Carboxylic Acid, a Highly Potent, Selective Leukotriene B4 Antagonist with Oral Activity in the Murine Collagen-Induced Arthritis Model

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of medicinal chemistry 1994-09, Vol.37 (20), p.3197-3199
Hauptverfasser:	Koch, Kevin, Melvin, Lawrence S, Reiter, Lawrence A, Biggers, Michael S, Showell, Henry J, Griffiths, Richard J, Pettipher, E. Roy, Cheng, John B, Milici, Anthony J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arthritis - chemically induced Arthritis - drug therapy Benzopyrans - chemical synthesis Benzopyrans - pharmacology Benzopyrans - therapeutic use Carboxylic Acids - chemical synthesis Carboxylic Acids - pharmacology Carboxylic Acids - therapeutic use Collagen Guinea Pigs Humans Leukotriene B4 - antagonists & inhibitors Leukotriene B4 - metabolism Mice Molecular Structure Neutrophils - metabolism Structure-Activity Relationship
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