Nanoclustered Cascaded Enzymes for Targeted Tumor Starvation and Deoxygenation-Activated Chemotherapy without Systemic Toxicity

Intratumoral glucose depletion-induced cancer starvation represents an important strategy for anticancer therapy, but it is often limited by systemic toxicity, nonspecificity, and adaptive development of parallel energy supplies. Herein, we introduce a concept of cascaded catalytic nanomedicine by c...

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Veröffentlicht in:	ACS nano 2019-08, Vol.13 (8), p.8890-8902
Hauptverfasser:	Ma, Yinchu, Zhao, Yangyang, Bejjanki, Naveen Kumar, Tang, Xinfeng, Jiang, Wei, Dou, Jiaxiang, Khan, Malik Ihsanullah, Wang, Qin, Xia, Jinxing, Liu, Hang, You, Ye-Zi, Zhang, Guoqing, Wang, Yucai, Wang, Jun
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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