A Pharmaceutical Industry Perspective on Sustainable Metal Catalysis

As companies grow ever more mindful of the sustainability aspects of their products and supply chains, an increasing focus on the environmental impact of pharmaceutical manufacture spurs innovation from chemists who support this industry. Metal catalysis has the potential to greatly enhance the sust...

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Veröffentlicht in:Organometallics 2019-01, Vol.38 (1), p.36-46
Hauptverfasser: Hayler, John D, Leahy, David K, Simmons, Eric M
Format: Artikel
Sprache:eng
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Zusammenfassung:As companies grow ever more mindful of the sustainability aspects of their products and supply chains, an increasing focus on the environmental impact of pharmaceutical manufacture spurs innovation from chemists who support this industry. Metal catalysis has the potential to greatly enhance the sustainability of pharmaceutical products, leading to shorter and more efficient synthetic routes and more direct access to single stereoisomeric products. This perspective article seeks to highlight a number of important considerations for the design of new and improved sustainable metal-catalyzed transformations in order to facilitate rapid adoption by the pharmaceutical industry.
ISSN:0276-7333
1520-6041
DOI:10.1021/acs.organomet.8b00566