Constructing a Library of Doubly Grafted Polymers by a One-Shot Cu-Catalyzed Multicomponent Grafting Strategy

Doubly grafted polymers bearing two different macromolecular side groups in each repeat unit of the polymer backbone have received considerable attention because of their unique molecular structures and properties. However, the preparation of these polymers is challenging because of the synthetic difficulty arising from their steric crowding and structural complexity. Here, based on the diversity-oriented polymerization concept, we report the synthesis of well-defined doubly grafted polymers at 30 °C using a one-shot Cu-catalyzed multicomponent grafting strategy using readily accessible precursor polymers possessing sulfonyl azides and alkyne and amine macromonomers. Based on this strategy, we prepared 35 doubly grafted polymers. Detailed 1H NMR and SEC analyses revealed high grafting efficiency (79–99%) and narrow-to-moderate dispersities of the well-defined doubly grafted polymers.