Spontaneous Solid-State Cocrystallization of Caffeine and Urea
The cocrystallization of caffeine and urea was monitored and analyzed using infrared spectroscopy, Raman microscopy, scanning electron microscopy, differential scanning calorimetry, and X-ray diffraction. The caffeine–urea cocrystal was shown to form spontaneously over several weeks under low energy...
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Veröffentlicht in: | Crystal growth & design 2020-02, Vol.20 (2), p.736-745 |
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Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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Zusammenfassung: | The cocrystallization of caffeine and urea was monitored and analyzed using infrared spectroscopy, Raman microscopy, scanning electron microscopy, differential scanning calorimetry, and X-ray diffraction. The caffeine–urea cocrystal was shown to form spontaneously over several weeks under low energy mixing of the solids at room temperature and low relative humidity ( |
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ISSN: | 1528-7483 1528-7505 |
DOI: | 10.1021/acs.cgd.9b01152 |