$Preserving toxicologic activity during chromatographic fractionation of bioactive complex mixtures$

Preserving toxicologic activity during chromatographic fractionation of bioactive complex mixtures

Four types of chromatographic materials were evaluated for degree of recovery of mutagenic components during column chromatography. Materials tested were silica, alumina, Florisil, and cyanopropyl-bonded silica. A combustion-generated complex mixture that was highly characterized and known to contai...

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Veröffentlicht in:	Anal. Chem.; (United States) 1986-03, Vol.58 (3), p.568-572
Hauptverfasser:	Lafleur, Arthur L, Braun, Andrew G, Monchamp, Peter A, Plummer, Elaine F
Format:	Artikel
Sprache:	eng
Schlagworte:	400102 - Chemical & Spectral Procedures ADSORPTION ALUMINIUM COMPOUNDS ALUMINIUM OXIDES Analytical chemistry Animals CHALCOGENIDES Chemistry Chromatographic methods and physical methods associated with chromatography CHROMATOGRAPHY Chromatography, Liquid DATA Drug Stability Exact sciences and technology EXPERIMENTAL DATA FRACTIONATION In Vitro Techniques INFORMATION INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY LIQUID COLUMN CHROMATOGRAPHY MATERIALS MINERALS Mutagenicity Tests MUTAGENS Mutagens - analysis Mutagens - isolation & purification Mutagens - toxicity NUMERICAL DATA Other chromatographic methods OXIDE MINERALS OXIDES OXYGEN COMPOUNDS Rats SEPARATION PROCESSES SILICA SILICON COMPOUNDS SILICON OXIDES SORPTION SORPTIVE PROPERTIES SURFACE PROPERTIES TOXIC MATERIALS TOXICITY
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