The human respiratory nasal mucosa in females using contraceptive pills: an ultramicroscopic and histochemical study

The ultrastructure and histochemical changes in 25 females using contraceptive pills were studied. Fifteen pill-using females developing no nasal symptoms showed similar changes to those observed in symptom-free pregnant females. Ten pill-using females developing nasal symptoms showed squamous metap...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of laryngology and otology 1984, Vol.98 (1), p.43-51
Hauptverfasser:	TOPPOZADA, H, TOPPOZADA, M, EL-GHAZZAWI, I, ELWANY, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Birth control Contraceptives, Oral, Combined - adverse effects Epithelium - drug effects Epithelium - ultrastructure Ethinyl Estradiol - adverse effects Female Gynecology. Andrology. Obstetrics Histocytochemistry Hormonal contraception Humans Hyperplasia - pathology Medical sciences Metaplasia - pathology Microscopy, Electron Nasal Mucosa - drug effects Nasal Mucosa - metabolism Nasal Mucosa - ultrastructure Norethindrone - adverse effects Rhinitis - chemically induced Rhinitis - pathology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The ultrastructure and histochemical changes in 25 females using contraceptive pills were studied. Fifteen pill-using females developing no nasal symptoms showed similar changes to those observed in symptom-free pregnant females. Ten pill-using females developing nasal symptoms showed squamous metaplasia, interepithelial oedema, glandular hyperplasia, histiocytic proliferation and fibrous tissue deposition, all attributed to the action of oestrogen. Their histochemical reactions were similar to those of chronic hypertrophic non-allergic rhinitis.
ISSN:	0022-2151 1748-5460
DOI:	10.1017/S002221510014616X