Evolving health monitoring: Nanoscale flexible electronics for noninvasive uric acid analysis in sweat

In the rapidly evolving field of health monitoring, nanoscale flexible electronics are proving crucial for noninvasive diagnostics. This review highlights significant advancements in detecting uric acid in sweat, a key biomarker for metabolic and renal disorders, using these technologies. We outline the development of precise, adaptable sensors enabled by nanomaterials, emphasizing their role in improving sensor specificity and sensitivity—crucial for effective disease management such as gout and kidney diseases. These technological innovations hold the potential to revolutionize personal health monitoring by integrating with wearable devices, offering a promising future for noninvasive medical diagnostics. [Display omitted] •This review introduces nanomaterials for uric acid detection in sweat.•Innovations in wearable sensor technology are detailed.•The focus is on enhancing real-time health monitoring.•The integration of noninvasive diagnostics is examined.•Advances in sensor precision and reliability are analyzed.