Advancements in metal organic framework-based materials for the detection of antioxidants in food and biological fluids

Antioxidants are key components in a multitude of food, plant, and pharmacological products. The quantitative, selective, and facile assessment of antioxidants has thus become crucial in evaluating the quality of such products and their health effects. In this respect, it is important to recognize the great potential of advanced materials, especially metal-organic frameworks (MOF) for the construction of highly efficient sensing platforms against antioxidants. In this article, the practical utility of MOFs is highlighted in the optical and electrochemical sensing of antioxidants in relation to their sensing mechanisms and performances (in terms LOD, sensing range, and detection time). The best MOF-based sensing platforms for antioxidants are after all recommended along with a discussion on the future of this technology. [Display omitted] •The sensing potentials of MOFs have been assessed against antioxidants.•MOF-based optical and electrochemical sensors are explored.•Basic QA parameters are examined to assess their sensing performances.•Mi-UiO-66 and Mi-UiO-67 are the best performers in terms of LOD.•Optical sensors are far more sensitive (e.g., 24 times) than electrochemical sensors.