n-Bu4NI/H2O2-catalyzed mild conversion of hydroxamic acids to carboxylic acids

n-Bu4NI/H2O2-catalyzed mild conversion of hydroxamic acids to carboxylic acids

[Display omitted] A variety of aromatic and aliphatic hydroxamic acids were transformed into carboxylic acids employing tetra-n-butylammonium iodide and hydrogen peroxide. The reaction was executed across a range of substrates encompassing diverse functional groups, delivering good to excellent yiel...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Tetrahedron letters 2023-08, Vol.126, p.154656, Article 154656
Hauptverfasser: Nakamura, Akira, Morimoto, Jyunya, Taniguchi, Maho, Aoyama, Haruka, He, Jiadong, Maegawa, Tomohiro
Format: Artikel
Sprache:eng
Schlagworte:
Acylnitoroso species
Carboxylic acids
Catalytic reaction
Hydrolysis
Hydroxamic acids
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:[Display omitted] A variety of aromatic and aliphatic hydroxamic acids were transformed into carboxylic acids employing tetra-n-butylammonium iodide and hydrogen peroxide. The reaction was executed across a range of substrates encompassing diverse functional groups, delivering good to excellent yields. This catalytic hydrolysis features gentle reaction conditions and the application of a non-hazardous, cleanly processed, and easy-to-manage oxidant.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2023.154656