Ancepsone A, a new cheilanthane sesterterpene from Aleuritopteris anceps

Ancepsone A, a new cheilanthane sesterterpene from Aleuritopteris anceps

[Display omitted] Ancepsone A, a new sesterterpene with 13,19-epoxycheilanthane skeleton, i.e (17Z)-13,19-epoxycheilanth-1,17-diene-2-ol-3-one (1), together with eight known natural products (2 ∼ 9) were isolated from Aleuritopteris anceps. The structure of the new compound was established by means...

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Veröffentlicht in:Tetrahedron letters 2022-06, Vol.100, p.153869, Article 153869
Hauptverfasser: Jiang, Tianju, Dai, Xiling, Gao, Ting, Wang, Lili, Yang, Fan, Zhang, Yu, Wang, Nina, Huang, Guozheng, Cao, Jianguo
Format: Artikel
Sprache:eng
Schlagworte:
Aleuritopteris anceps
Ancepsone A
Cheilanthane
Cytotoxicity
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Zusammenfassung:[Display omitted] Ancepsone A, a new sesterterpene with 13,19-epoxycheilanthane skeleton, i.e (17Z)-13,19-epoxycheilanth-1,17-diene-2-ol-3-one (1), together with eight known natural products (2 ∼ 9) were isolated from Aleuritopteris anceps. The structure of the new compound was established by means of 1D and 2D NMR, MS, and single-crystal X-ray diffraction methods. All compounds were isolated from A. anceps for the first time. Ancepsone A and the isolated flavonoids can moderately inhibit the proliferation of cancer cells.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2022.153869