Direct synthesis of regioselective α-allyl α-selanyl ketones and selanyl tetra-hydrofurans

[Display omitted] •One pot three-component synthesis of α-allyl α-selanyl ketones and selanyl tetra-hydrofurans.•Ambient temperature of 35 °C.•Facile oxidative elimination delivers the trans-1,3-dienone. An efficient approach for the synthesis of α-allyl α-selanyl ketone and selanyl tetrahydrofurans...

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Veröffentlicht in:Tetrahedron letters 2020-05, Vol.61 (22), p.151920, Article 151920
Hauptverfasser: Sahoo, Sushree Ranjan, Singh, Rajat Kumar, Sarkar, Debayan
Format: Artikel
Sprache:eng
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Zusammenfassung:[Display omitted] •One pot three-component synthesis of α-allyl α-selanyl ketones and selanyl tetra-hydrofurans.•Ambient temperature of 35 °C.•Facile oxidative elimination delivers the trans-1,3-dienone. An efficient approach for the synthesis of α-allyl α-selanyl ketone and selanyl tetrahydrofurans has been reported in this present work. The sodium methoxide (MeONa) mediated one pot three-component synthesis lead towards a good to an excellent yield of products with a wide substrate scope. The selenylated ketones can be important point towards important organic synthons.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2020.151920