Direct synthesis of regioselective α-allyl α-selanyl ketones and selanyl tetra-hydrofurans
[Display omitted] •One pot three-component synthesis of α-allyl α-selanyl ketones and selanyl tetra-hydrofurans.•Ambient temperature of 35 °C.•Facile oxidative elimination delivers the trans-1,3-dienone. An efficient approach for the synthesis of α-allyl α-selanyl ketone and selanyl tetrahydrofurans...
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Veröffentlicht in: | Tetrahedron letters 2020-05, Vol.61 (22), p.151920, Article 151920 |
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Hauptverfasser: | , , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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•One pot three-component synthesis of α-allyl α-selanyl ketones and selanyl tetra-hydrofurans.•Ambient temperature of 35 °C.•Facile oxidative elimination delivers the trans-1,3-dienone.
An efficient approach for the synthesis of α-allyl α-selanyl ketone and selanyl tetrahydrofurans has been reported in this present work. The sodium methoxide (MeONa) mediated one pot three-component synthesis lead towards a good to an excellent yield of products with a wide substrate scope. The selenylated ketones can be important point towards important organic synthons. |
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ISSN: | 0040-4039 1873-3581 |
DOI: | 10.1016/j.tetlet.2020.151920 |