Gold(III)-catalyzed regioselective synthesis of vinyl-substituted pyrazolo[1,4]-oxazepines via 7-exo-trig cyclization

Vinyl-substituted pyrazo[1,4]-oxazepines were prepared through an intramolecular regioselective cyclization method under gold catalysis. This organic transformation achieved selective C–N bond formation via 7-exo-trig cyclization, resulting in vinyl-containg pyrazolo[1,4]-benzooxazepines and pyrazolo[1,4]-naphthoxazepines in one-pot with moderate to very good yields. [Display omitted]