Diastereoselective cycloaddition of isatin derived azomethine ylides to 3-nitro-2(1H)-quinolones

The 1,3-dipolar cycloaddition of 3-nitro-2(1H)-quinolones with azomethine ylides derived from sarcosine or thiazolidine-4-carboxylic acid and various 1H-indole-2,3-diones (isatins) have been investigated. The structure and stereochemistry of the formed cycloadducts were studied in detail by X-ray di...

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Veröffentlicht in:	Tetrahedron 2024-03, Vol.153, p.133848, Article 133848
Hauptverfasser:	Molnár, Márk, Balázs, Barbara, Bényei, Attila, Nyerges, Miklós
Format:	Artikel
Sprache:	eng
Schlagworte:	1,3-Dipolar cycloaddition Azomethine ylide Quinoline Stereoselectivity X-ray diffraction
Online-Zugang:	Volltext
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Zusammenfassung:	The 1,3-dipolar cycloaddition of 3-nitro-2(1H)-quinolones with azomethine ylides derived from sarcosine or thiazolidine-4-carboxylic acid and various 1H-indole-2,3-diones (isatins) have been investigated. The structure and stereochemistry of the formed cycloadducts were studied in detail by X-ray diffraction and NMR spectroscopy methods. [Display omitted]
ISSN:	0040-4020 1464-5416
DOI:	10.1016/j.tet.2024.133848