Mesenchymal chondrosarcoma of the foot salvaged by sensate chimeric anterolateral thigh free flap

Mesenchymal chondrosarcoma is a rare, aggressive sarcoma of bone or soft tissue with a high risk of hematogenous spread, leading to significant morbidity and mortality. Surgical resection is the standard treatment for localized cases. Addressing the limited data, we present a case of localized mesenchymal chondrosarcoma in the foot, where upfront surgery risked sacrificing the medial longitudinal arch crucial for weight-bearing. The patient received neoadjuvant chemotherapy and underwent limb salvage surgery using a sensate chimeric anterolateral thigh flap to preserve functionality.