NSAIDs and anastomotic leak: What's the evidence?

NSAIDs and anastomotic leak: What's the evidence?

Non-steroidal anti-inflammatory drugs (NSAIDs) are effective analgesics and may be a valuable component of opioid-sparing perioperative analgesic strategies following colorectal surgery. However, NSAIDs may also impair wound healing and have been associated with an increased risk of anastomotic leak...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Seminars in colon and rectal surgery 2021-09, Vol.32 (3), p.100833, Article 100833
Hauptverfasser: Lee, Lawrence, Fiore, Julio F.
Format: Artikel
Sprache:eng
Schlagworte:
Anastomotic leak
Colorectal surgery
NSAIDs
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Non-steroidal anti-inflammatory drugs (NSAIDs) are effective analgesics and may be a valuable component of opioid-sparing perioperative analgesic strategies following colorectal surgery. However, NSAIDs may also impair wound healing and have been associated with an increased risk of anastomotic leak in some reports. In this chapter we will review the benefits of NSAIDs in managing postoperative pain, and review and critique the body of evidence on the association between NSAIDs and anastomotic leaks after colorectal surgery.
ISSN:1043-1489
1558-4585
DOI:10.1016/j.scrs.2021.100833