Effects of nanoparticles on neuroinflammation in a mouse model of asthma

•Nanoparticles exaggerate allergic airway inflammation.•Neurogenic inflammation in the lung involves an increase in neurogenic inflammatory mediators causing to exacerbation of asthma.•TRPV1, TRPV4, P2X4, and P2X7 be involved in the pathogenesis of bronchial asthma and nanoparticles. The interaction between chronic inflammation and neural dysfunction points to a link between the nervous and immune systems in the airways. In particular, environmental exposure to nanoparticles (NPs), defined as particulate matter having one dimension