On the optical characterization and biological implications of titania phases

Transformation process of TiO2 from anatase to rutile phase upon annealing affects its optical and biological implications. In the present work; TiO2 is synthesized by sol-gel technique. The optical and biological implications were depicted through the transformation process covering the range of 350–800 °C. Raman spectroscopy applied for depicting the structural analysis. The absorption coefficient, optical band gap energies, extinction coefficient and color strength were calculated as a function of annealing temperature. Moreover, Biological implications were followed by immersion tests within DMEM for 72 h. The results showed variable changes in the optical parameter values upon annealing due to the induced structural changes in the TiO2 network. The biological implications proved successful formation of a new Ca–P depletion layer post 48 h immersion with priority for anatase. The results proved the apparent effect of annealing temperature on the structural, optical and biological activity. Therefore, TiO2 desired properties can be tailored. [Display omitted] •TiO2 is synthesized by sol-gel to study the effect of annealing temperature from 300 ̊C to 800 ̊C on its structure, optical characterization and biological implications.•Transformation from anatase to rutile phase starts at 500 ̊C as depicted by Raman analysis.•The variations in the optical parameters, including the tristimulus reflectance, color parameters, and chromaticity diagram, reflect the changes in the TiO2 structural network.•The osteo-conduction capability of both anatase and rutile phases is confirmed through formation of New apatitic layer post 72 h immersion within DMEM.