Combinatorial immunotherapy with anti-ROR1 CAR NK cells and an IL-21 secreting oncolytic virus against neuroblastoma

Combinatorial immunotherapy with anti-ROR1 CAR NK cells and an IL-21 secreting oncolytic virus against neuroblastoma

Children with recurrent/metastatic neuroblastoma (NB) have a dismal survival (

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Bibliographische Detailangaben
Veröffentlicht in:Molecular Therapy: Oncology 2025-03, Vol.33 (1), p.200927, Article 200927
Hauptverfasser: Chu, Yaya, Tian, Meijuan, Saini, Uksha, Ayala-Cuesta, Jessica, Klose, Kayleigh, Mendelowitz, Alyssa S., Foley, Keira, Ozkaynak, Mehmet F., Luo, Wen, Cripe, Timothy P., Lee, Dean A., Cassady, Kevin A., Cairo, Mitchell S.
Format: Artikel
Sprache:eng
Schlagworte:
CAR
chimeric antigen receptor
natural killer cells
neuroblastoma
oncolytic herpes simplex virus
ROR1
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Zusammenfassung:Children with recurrent/metastatic neuroblastoma (NB) have a dismal survival (
ISSN:2950-3299
2950-3299
DOI:10.1016/j.omton.2024.200927