Metabolic regulation and the anti-obesity perspectives of brown adipose tissue (BAT); a systematic review

Obesity is a disease that body energy intake is more than energy expenditure. In rodents and humans, there are two types of adipose tissue: White adipose tissue and Brown adipose tissue. Whereas WAT stores excess energy as triacylglycerols, BAT is specialized in the production of heat. PubMed and Cochrane databases were searched using the related keywords to find related documents published until August 2019. In total, 115 published reports were reviewed in the study. Obesity associated with different diseases such as type 2 diabetes, cardiovascular disease, hypertension, stroke, arthritis, and various types of cancer. Until recent years, it treated in various ways, such as diet, physical activity, using medications, and surgical procedures. In recent years, Brown adipose tissue has been recognized as a way to combat obesity and metabolic regulation. Recent years are challenging times for all those working in the field of obesity and the pace of discovery about obesity than ever before. During the last decades, many notable discoveries resulting from the active research into the pathophysiological mechanisms controlling food intake, energy expenditure, and body fat mass have been produced. Potential new avenues are opened for the future treatment of obesity by the recent findings and its related disorders, although finding practical solutions to the problems posed by obesity could ultimately depend as much on clever science and good clinical practice as on actively engaging the individual and society alike to change everyday lifestyle. •New ideas for treating obesity by brown adipose tissue (BAT) help.•Effect of brown adipose tissue (BAT) Affect Body Performance