Real-time digital signal processing implementation for in-beam PET of radiotherapy imaging in HIMM

The in-beam positron emission tomography (ibPET) is dedicated to radiotherapy imaging of the heavy-ion medical machine (HIMM), which requires precise online measurement, as well as real-time signal processing capability of the electronics. In this paper, we present the implementation of real-time digital signal processing in the data acquisition unit (DAQU) for an ibPET system based on the photomultiplier tube (PMT) readout of lutetium-yttrium oxyorthosilicate (LYSO) scintillator crystals. We have designed 10-channel customized signal processing circuit on a high-performance FPGA, which supports 3 working modes (single event processing mode, self-calibration mode and raw ADC data mode), position calculation, crystal locating, event sorting, and etc. Moreover, the implementation of real-time corrections is capable of dealing with photon peak correction to 511 keV and crystal ID-based time correction. The implemented real-time ibPET system can achieve 46% data compression and beyond 1,000,000 events/sec/channel signal processing capabilities. A series of initial tests is conducted, and the results indicate that this design meets the application requirement on online processing.