Unlocking potential of zinc oxide nanoparticles in enhancing topical drug delivery

This review explores the pivotal role of zinc oxide nanoparticles in advancing modern topical drug delivery. Delving into topical drug delivery systems, it addresses the significance, challenges, and current trends. The section on zinc oxide nanoparticles provides a comprehensive overview, encompassing their properties, synthesis methods, and characterization techniques, highlighting their unique advantages in drug delivery. The focal point of the review is the multifaceted application of zinc oxide nanoparticles in topical drug delivery, showcasing their effectiveness in anti-inflammatory treatments, psoriasis management, combating skin cancer, antibacterial interventions, and promoting wound healing. Intradermal application of zinc oxide nanoparticles demonstrated notable efficacy in diminishing skin infection, lowering bacterial burden, and alleviating inflammation, concurrently fostering enhancement in the structural integrity of the infected skin. To recapitulate the remarkable properties of zinc oxide nanoparticles, offer an excellent alternative for revolutionizing topical drug delivery. Their enhanced permeation, stability, and biocompatibility offer tremendous potential for improving therapeutic outcomes. [Display omitted]