A pH-responsive citric-acid/α-cyclodextrin-functionalized Fe3O4 nanoparticles as a nanocarrier for quercetin: An experimental and DFT study

A pH-responsive citric-acid/α-cyclodextrin-functionalized Fe3O4 nanoparticles as a nanocarrier for quercetin: An experimental and DFT study

Developing new nanocarriers and understanding the interactions between the drug and host molecules in the nanocarrier at the molecular level is of importance for future of nanomedicine. In this work, we synthesized and characterized a series of iron oxide nanoparticles (IONPs) functionalized with di...

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Veröffentlicht in:Materials Science & Engineering C 2020-04, Vol.109, p.110597, Article 110597
Hauptverfasser: Ghafelehbashi, Robabehbeygom, Tavakkoli Yaraki, Mohammad, Heidarpoor Saremi, Leily, Lajevardi, Aseman, Haratian, Masoud, Astinchap, Bandar, Rashidi, Ali Mohammad, Moradian, Rostam
Format: Artikel
Sprache:eng
Schlagworte:
Density functional theory
Drug delivery
Magnetic
Quercetin
Stimuli-responsive
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Zusammenfassung:Developing new nanocarriers and understanding the interactions between the drug and host molecules in the nanocarrier at the molecular level is of importance for future of nanomedicine. In this work, we synthesized and characterized a series of iron oxide nanoparticles (IONPs) functionalized with different organic molecules (citric acid, α-cyclodextrin, and citric acid/α-cyclodextrin composite). It was found that incorporation of citric acid into the α-cyclodextrin had negligible effect on the adsorption efficiency (
ISSN:0928-4931
1873-0191
DOI:10.1016/j.msec.2019.110597