Hydrolyzed Arabic gum-grafted-polyacrylonitrile@ zinc ferrite nanocomposite as an efficient biocatalyst for the synthesis of pyranopyrazoles derivatives

•Hydrolyzed Arabic gum-grafted-polyacrylonitrile@zinc ferrite biocatalyst was faricated.•Biocatalyst employed for the synthesis of pyranopyrazoles derivatives.•Highest yield of dihydropyrano [2,3-c] pyrazole obtained by biocatalyst in a green solvent.•High catalytic activity, good yields, and fast reaction time were benefits of biocatalyst. A catalytic methodology for the effective synthesis of pyrazolopyrazole derivatives using a combination of hydrolyzed Arabic gum-g-polyacrylonitrile/ZnFe2O4 (Hyd AG-g-PAN/ZnFe2O4) catalyst, malononitrile, and aromatic aldehyde, hydrazine hydrate, and ethyl acetoacetate is described. This protocol relies on the use of environment-friendly heterogeneous catalyst based on zinc ferrite magnetic particles in combination with Arabic gum (AG) as the backbone, N, N methylene bisacrylamide (MBA) as a crosslinking agent, ammonium persulfate (APS) as an initiator, and alkaline solution for hydrolyzation. This bio-based catalyst with a soft three-dimensional cross-linked framework contains distinct acidic and basic sites and could be applied as a powerful catalyst for the one-pot synthesis of pyranopyrazoles derivatives. Using an external magnet, the superparamagnetic nanocomposite could be easily separated. Furthermore, the catalyst can well be utilized at least six times in subsequent reaction cycles before losing its activity. FT-IR, EDX, TGA, FESEM, VSM, and XRD methods were used to characterize the produced catalyst. Taking 0.01 g of catalyst at 80 °C in a green solvent of water/ethanol, the greatest output of dihydropyrano [2,3-c] pyrazole was 96% in 15 min. A simple technique, short reaction time, high yield, and the catalyst's reusability and stability are just a few of the study's advantages. [Display omitted]