Click generated o-Cresolphthalein linked 1,2,3-triazole derivative for selective Pb(II) ion recognition

Present report describes the “turn-on” absorbance response of a molecular assembly o-Cresolphthalein appended 1,4-disubstituted 1,2,3-triazole (o-CPT) on complexation with Pb(II) ions. Copper (I) catalyzed alkyne-azide cycloaddition reaction, a highly versatile and stereoselective approach to stitch diverse structural units has been employed to generate the designed receptor that has been successfully characterized through IR, NMR (1H, 13C) and mass spectroscopic techniques. UV-Visible absorption spectral behavior of o-CPT was examined with a series of metal ions (Mn (II), Ce (III), Hg (II), Ni (II), Pb (II), Zn (II), Fe (II), Cr (III), Co (II) and Na (I)) in acetonitrile-water (4:1, v/v) solution and the results obtained have marked out the sensitivity of the designed probe exclusively towards Pb(II) ions with a measured detection limit of 13 µM at 2:1 stoichiometry of o-CPT:Pb(II) complex. [Display omitted]