Solubilization of aqueous-insoluble phenothiazine drug in TX-100 micellar solution and interactions of cationic/anionic surfactants with phenothiazine–TX-100 system

Solubilization of aqueous-insoluble phenothiazine drug in TX-100 micellar solution and interactions of cationic/anionic surfactants with phenothiazine–TX-100 system

[Display omitted] •Solubilization of poorly soluble phenothiazine (PTZ) drug in TX-100 micellar aqueous solution.•The interaction of surfactants (TTAB/CTAB/CPC/CPB and SDS) in PTZ–TX-100 aqueous medium is studied.•The CMC values of studied surfactants in PTZ–TX-100 aqueous medium follow the sequence...

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Veröffentlicht in:Journal of molecular liquids 2022-05, Vol.354, p.118823, Article 118823
Hauptverfasser: Lalthlengliani, Jacqueline, Gurung, Jackson, Pulikkal, Ajmal Koya
Format: Artikel
Sprache:eng
Schlagworte:
Conductivity
Degree of counterion dissociation
Micellization
Phenothiazine drug
Solubilization
Surfactant
Thermodynamics
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Zusammenfassung:[Display omitted] •Solubilization of poorly soluble phenothiazine (PTZ) drug in TX-100 micellar aqueous solution.•The interaction of surfactants (TTAB/CTAB/CPC/CPB and SDS) in PTZ–TX-100 aqueous medium is studied.•The CMC values of studied surfactants in PTZ–TX-100 aqueous medium follow the sequence CTAB 
ISSN:0167-7322
1873-3166
DOI:10.1016/j.molliq.2022.118823