BSA adsorption, anthelmintic activity and swelling behavior of poly (N-cyclohexyl acrylamide-co-AMPS IL)hydrogel

In this study, the ionic liquid based hydrogels were synthesized by free radical polymerization. About 0.1 g of dried hydrogel placed in 20 ml of solution containing 4.0 mg/ml of BSA in BR buffer (various pH level) and allowed to equilibrate the swelling at 30 °C. The maximum protein separation 76.1...

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Veröffentlicht in:Journal of molecular liquids 2020-09, Vol.314, p.113692, Article 113692
Hauptverfasser: Kayalvizhy, E., Rajan, Mekha Susan, Pazhanisamy, P.
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Sprache:eng
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Zusammenfassung:In this study, the ionic liquid based hydrogels were synthesized by free radical polymerization. About 0.1 g of dried hydrogel placed in 20 ml of solution containing 4.0 mg/ml of BSA in BR buffer (various pH level) and allowed to equilibrate the swelling at 30 °C. The maximum protein separation 76.1% was achieved at pH 5.0 in room temperature. The hydrogels with various feed compositions possess good antibacterial as well as antifungal activity. The anthelmintic activity of hydrogels suggested that it can be effective against parasitic infections of humans. The DPPH scavenging assay results showed 89.44% of ionic liquid hydrogel as an antioxidant agent. •Ionic liquid based hydrogels were showed the maximum BSA protein separation 76.1% was achieved at pH 5.0.•Hydrogels exhibited good antibacterial, antifungal activity and 89. 44% antioxidant activity.•Anthelmintic activity of hydrogels showed more active against parasitic infections of humans.
ISSN:0167-7322
1873-3166
DOI:10.1016/j.molliq.2020.113692