Synthesis of core-shell-like structure SnS2-SnO2 integrated with graphene nanosheets for the electrochemical detection of furazolidone drug in furoxone tablet

Trace level evaluation in analysis is an important step to construct a viable sensor. Here, the proposed furazolidone (FZD) sensor was developed electrochemically using an SnS2-SnO2/graphene composite. The formation of the SnS2-SnO2/graphene composite was confirmed by physical characterizations such as X-ray crystallography (XRD), Scanning Electron Microscope (SEM), and Fourier Transform InfraRed (FT-IR) Spectroscopy. The newly synthesized SnS2-SnO2/graphene composite was drop-casted on a glassy carbon electrode (GCE) surface to investigate the electrochemical oxidation of FZD using cyclic voltammetry (CV) and differential pulse voltammetry (DPV) methods with the best working potential at −0.516 (vs. Ag/AgCl) in 0.1 M PB solution (pH 7.0). Using CV, different modified electrodes, different addition, scan rates, and pH studies were investigated to study peak current effects. The obtained DPV results at the SnS2-SnO2/graphene composite exhibited a lower limit of detection (LOD) (1.42 nM), good linear range, high selectivity, short-time response (˂1 s), better repeatability, reproducibility, and enduring stability. In addition, the fabricated SnS2-SnO2/graphene/GCE was used to determine the FZD in a commercially available furoxone tablet. [Display omitted] •Core-shell-like structure was derived by preparing SnS2-SnO2 heterostructure.•SnS2-SnO2 encapsulated with graphene was applied for the determination of furazolidone.•Effects of different modified electrodes, addition, scan rates and pH were inspected.•A DPV technique used to determine furazolidone with the lowermost detection limit.•Fabricated SnS2-SnO2/graphene electrode can be successfully implied for the real time application.