Cutaneous leukocytoclastic vasculitis at diagnosis of hairy cell leukemia successfully treated with vemurafenib and rituximab

Cutaneous leukocytoclastic vasculitis at diagnosis of hairy cell leukemia successfully treated with vemurafenib and rituximab

•Vasculitis is a relatively rare manifestation of hairy cell leukemia (HCL).•Vasculitis can be diagnosed as initial manifestation of HCL.•Cladribine is contraindicated in HCL patients with severe neutropenia, fever and infection.•Vemurafenib treatment is safe and effective in HCL patients with leuko...

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Veröffentlicht in:Leukemia research 2021-05, Vol.104, p.106571, Article 106571
Hauptverfasser: Robak, Ewa, Jesionek-Kupnicka, Dorota, Iskierka-Jazdzewska, Elzbieta, Janus, Agnieszka, Robak, Tadeusz
Format: Artikel
Sprache:eng
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Zusammenfassung:•Vasculitis is a relatively rare manifestation of hairy cell leukemia (HCL).•Vasculitis can be diagnosed as initial manifestation of HCL.•Cladribine is contraindicated in HCL patients with severe neutropenia, fever and infection.•Vemurafenib treatment is safe and effective in HCL patients with leukocytoclastic vasculitis.
ISSN:0145-2126
1873-5835
DOI:10.1016/j.leukres.2021.106571