The prostate as a good candidate organ for proving amyloid deposition in non-endemic late onset hereditary transthyretin amyloidosis: Report of two cases

•Amyloid fibrils deposit in the prostatic stroma in hereditary transthyretin amyloidosis (ATTRv) patients.•Late-onset male ATTRv patients commonly present with dysuria with various pathogenesis.•Analyzing prostatic tissue is useful to prove amyloid deposition and evaluate urinary disturbance in late...

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Veröffentlicht in:Journal of the neurological sciences 2021-05, Vol.424, p.117418, Article 117418
Hauptverfasser: Maeda, Kentaro, Kubota, Yasuaki, Kitagawa, Satoshi, Ueda, Mitsuharu, Ando, Yukio, Ito, Yasuhiro
Format: Artikel
Sprache:eng
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Zusammenfassung:•Amyloid fibrils deposit in the prostatic stroma in hereditary transthyretin amyloidosis (ATTRv) patients.•Late-onset male ATTRv patients commonly present with dysuria with various pathogenesis.•Analyzing prostatic tissue is useful to prove amyloid deposition and evaluate urinary disturbance in late-onset male ATTRv patients.
ISSN:0022-510X
1878-5883
DOI:10.1016/j.jns.2021.117418