Thermodynamics study and micellization behavior of surface active ionic liquid choline oleate in presence and absence of naproxen drug in alcoholic media at different temperatures: A conductometric and physicochemical analysis

Surface active ionic liquids (SAILs) have attracted significant interest as promising substitutes for conventionally available surfactants owing to their exceptionally favorable physicochemical features. Herein, the aggregation behavior of SAIL choline oleate (SAIL[Cho][Ole]) in the presence and absence of naproxen (NAP) drug and its interaction with alcohol such as methanol, ethanol, 2-propanol and 1-butanol at different concentrations and temperatures have been investigated by conductivity method. For alcohol-water systems at a fixed temperature, the critical micelle concentration (CMC) at a specific temperature was found to increase in the presence of alcoholic media. Finally, numerous thermodynamic parameters like standard Gibbs free energy of micellization (ΔGm°), standard enthalpy (ΔHm°), and standard entropy of micellization (ΔSm°) were calculated as well as explained thoroughly. The obtained negative values of ΔGm° and ΔHm° indicate that micellization is spontaneous and exothermic, respectively. The molar heat capacity (ΔCm0) was also evaluated as well as explained. •Synthesized SAIL[Cho][Ole] and explored its physicochemical features with naproxen (NAP) drug.•The physicochemical and thermodynamic properties of [Cho][Ole]/[Cho][Ole]+NAP mixed system have been investigated.•The CMC value of SAIL[Cho][Ole] increases with an increase in temperature for all systems.•Various types of physicochemical parameters (ΔGm°,ΔHm°,ΔSm°,andΔCm°) have been evaluated.•The processes of micellization were found energetically spontaneous and exothermic.