Inorganic arsenic toxicity and alleviation strategies in rice

Direct or indirect exposure to inorganic arsenic (iAs) in the forms of AsIII (arsenite) and AsV (arsenate) through consumption of As-contaminated food materials and drinking water leads to arsenic poisoning. Rice (Oryza sativa L.) plant potentially accumulates a high amount of iAs from paddy fields than any other cereal crops. This makes it to be a major source of iAs especially among the population that uses it as their dominant source of diet. The accumulation of As in human bodies poses a serious global health risk to the human population. Various conventional methods have been applied to reduce the arsenic accumulation in rice plant. However, the success rate of these techniques is low. Therefore, the development of efficient and effective methods aimed at lowering iAs toxicity is a very crucial public concern. With the current advancement in technology, new strategies aimed at addressing this concern are being developed and utilized in various parts of the world. In this review, we discuss the recent advances in the management of iAs in rice plants emphasizing the use of nanotechnology and biotechnology approaches. Also, the prospects and challenges facing these approaches are described. [Display omitted] •Inorganic arsenic (iAs) poses a serious global health risk to the human population due to its toxic and carcinogenic nature.•The recent advances in the alleviation of iAs toxicity in rice plant are reviewed.•Application of biotechnology and nanotechnology strategies in the management of iAs toxicity in rice plant are reported.•Challenges limiting the applicability of these strategies are discussed.•Future research directions that can be utilized in managing iAs toxicity in rice plant have also been proposed.