Clozapine loaded nanostructured lipid carriers engineered for brain targeting via nose-to-brain delivery: Optimization and in vivo pharmacokinetic studies

Clozapine loaded nanostructured lipid carriers engineered for brain targeting via nose-to-brain delivery: Optimization and in vivo pharmacokinetic studies

Clozapine is commonly used to treat schizophrenia but it is having issues of low oral bioavailability (

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Veröffentlicht in:Journal of drug delivery science and technology 2021-08, Vol.64, p.102533, Article 102533
Hauptverfasser: Patel, Hetal P., Gandhi, Priyanshi A., Chaudhari, Priyanka S., Desai, Bhargavi V., Desai, Ditixa T., Dedhiya, Praful P., Maulvi, Furqan A., Vyas, Bhavin A.
Format: Artikel
Sprache:eng
Schlagworte:
Clozapine
Life Sciences & Biomedicine
Nanostructured lipid carrier
Nose-to-brain
Optimization
Pharmacokinetic
Pharmacology & Pharmacy
Schizophrenia
Science & Technology
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Beschreibung
Zusammenfassung:Clozapine is commonly used to treat schizophrenia but it is having issues of low oral bioavailability (
ISSN:1773-2247
2588-8943
DOI:10.1016/j.jddst.2021.102533