Bioavailability enhancement of repaglinide from transdermally applied nanostructured lipid carrier gel: Optimization, in vitro and in vivo studies

Bioavailability enhancement of repaglinide from transdermally applied nanostructured lipid carrier gel: Optimization, in vitro and in vivo studies

Repaglinide (RG) is an effective anti-diabetic drug (BCS class II) with limited oral bioavailability 

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Veröffentlicht in:Journal of drug delivery science and technology 2020-06, Vol.57, p.101731, Article 101731
Hauptverfasser: Pandey, Sonia S., Patel, Mayuri A., Desai, Ditixa T., Patel, Hetal P., Gupta, Arti R., Joshi, Shrikant V., Shah, Dinesh O., Maulvi, Furqan A.
Format: Artikel
Sprache:eng
Schlagworte:
Bioavailability
Box behnken design
Nanostructure lipid carrier
Repaglinide
Transdermal delivery
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Zusammenfassung:Repaglinide (RG) is an effective anti-diabetic drug (BCS class II) with limited oral bioavailability 
ISSN:1773-2247
DOI:10.1016/j.jddst.2020.101731