Albumin nanoparticles as nanocarriers for drug delivery: Focusing on antibody and nanobody delivery and albumin-based drugs

Given that albumin has important roles in human body, it can be used in the field of medicine and disease treatment. In recent years, albumin is used as a carries in disease diagnosis and treatment. Therapeutic drugs have some disadvantages such as low solubility, shallow absorption and many side ef...

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Veröffentlicht in:Journal of drug delivery science and technology 2020-02, Vol.55, p.101471, Article 101471
Hauptverfasser: Karami, Elmira, Behdani, Mahdi, Kazemi-Lomedasht, Fatemeh
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Sprache:eng
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Zusammenfassung:Given that albumin has important roles in human body, it can be used in the field of medicine and disease treatment. In recent years, albumin is used as a carries in disease diagnosis and treatment. Therapeutic drugs have some disadvantages such as low solubility, shallow absorption and many side effects all of which can be overcome using nanocarriers like albumin. In this article, we reviewed different types of albumin (human, bovine, and egg) and various methods in producing and transporting albumin. We also discussed the ability of albumin as nanoparticle in reducing drug side effects and increasing their stability. [Display omitted]
ISSN:1773-2247
DOI:10.1016/j.jddst.2019.101471