Manufacturing of Ag/Ag2O nanocomposites for anti-quorum sensing: A Safe and green approach

•AgNPs are successfully manufactured from H. capitatum flower extract by the eco-friendly, efficient, novel, and rapid method of green synthesis.•Due to the partial ionization of phenolic substances as reducing agents, well-crystallized cubic phase Ag/Ag2O nanocomposites formed.•Ag/Ag2O nanocomposites showed significant anti-quorum sensing activity on C. violaceum and P. aeruginosa. Green synthesis of silver nanoparticles is the most phenomena topic that has affected all aspects of nanotechnology research, especially modern material sciences. The current study focuses on using endemic Hypercium capitatum in silver nanocomposite synthesis and investigating quorum quenching effects on Choromobacter violaceum and Pseudomonas aeruginosa. The strong absorption SPR peak appeared at about 432 nm. The optical bandgap of Ag/Ag2O nanocomposites was predicted as about 1.95 eV by Tauc’s plot equation. The size distribution of Ag/Ag2O nanocomposites with spherical shape ranged from 20.55 nm to 30.76 nm by SEM images. XRD findings confirmed the pure crystalline nature of biogenic Ag/Ag2O nanocomposites with an average 30 nm size. FTIR spectrum indicated the presence of bioactive functional components responsible for the bioreduction of bulk AgNO3 to Ag/Ag2O nanocomposites. The Ag/Ag2O nanocomposites effectively inhibited the pyocyanin and violacein-producing controlled by quorum sensing. This could be a promising achievement in a struggle with many persistent and dynamic pathogens.