Exploring the intersection of albinism and Trichilemmal carcinoma: A case of bilateral trichilemmal carcinoma in the axilla

Albinism is an autosomal recessive disorder characterized by the absence of melanin in the skin, albinism has a prevalence of 1 in 1000 in sub-Saharan Africa, with a lack of melanin increased risk of skin malignancy. Trichlemmal carcinoma is a rare malignant adnexal tumor mostly in sun-exposed areas. We are presenting a case of a 35-year-old albino patient with a previous history of squamous cell carcinoma with full recovery. Presented with bilateral axillary masses with no other finding in history or examination. Short period deference between the two tumors with rapidly growing course. Both tumors were excised but in different operations, one covered with latissimus dorsi and the other primarily. Both tumor histopathologies revealed trichilemmal carcinoma with a free tumor margin. Albinism, caused by tyrosine deficiency and characterized by a lack of melanin, significantly increases susceptibility to ultraviolet (UV) radiation and skin cancers, particularly squamous cell carcinoma (SCC) and basal cell carcinoma (BCC). Trichlmmal carcinoma TLC, an uncommon malignancy from hair follicle structures, is notably rare, comprising