Introduction of human-centric AI assistant to aid radiologists for multimodal breast image classification

•User study findings of 45 physicians comprising nine clinical institutions.•List of design recommendations for visualization to support breast screening radiomics.•Evaluation results of a proof-of-concept BreastScreening prototype for two conditions Current (without AI assistant) and AI-Assisted.•Evidence from the impact of a Multimodality and AI-Assisted strategy in diagnosing and severity classification of lesions. In this research, we take an HCI perspective on the opportunities provided by AI techniques in medical imaging, focusing on workflow efficiency and quality, preventing errors and variability of diagnosis in Breast Cancer. Starting from a holistic understanding of the clinical context, we developed BreastScreening to support Multimodality and integrate AI techniques (using a deep neural network to support automatic and reliable classification) in the medical diagnosis workflow. This was assessed by using a significant number of clinical settings and radiologists. Here we present: i) user study findings of 45 physicians comprising nine clinical institutions; ii) list of design recommendations for visualization to support breast screening radiomics; iii) evaluation results of a proof-of-concept BreastScreening prototype for two conditions Current (without AI assistant) and AI-Assisted; and iv) evidence from the impact of a Multimodality and AI-Assisted strategy in diagnosing and severity classification of lesions. The above strategies will allow us to conclude about the behaviour of clinicians when an AI module is present in a diagnostic system. This behaviour will have a direct impact in the clinicians workflow that is thoroughly addressed herein. Our results show a high level of acceptance of AI techniques from radiologists and point to a significant reduction of cognitive workload and improvement in diagnosis execution.