A new biopsychosocial questionnaire (BETY-BQ) for patients with ankylosing spondylitis

•Scale evaluating the biopsychosocial status in Ankylosing Spondylitis (AS) is needed.•A valid, reliable, and responsive biopsychosocial scale for individuals with AS has been presented.•Cognitive Exercise Therapy Approach-Biopsychosocial Questionnaire (BETY-BQ) is useful in healthcare and research.•BETY-BQ provides easy, comprehensive evaluation of individuals with AS. Scales for biopsychosocial evaluation of patients are limited. This study assessed the validity, reliability, and responsiveness of a Cognitive Exercise Therapy Approach-Biopsychosocial Questionnaire (Bilişsel Egzersiz Terapi Yaklaşımı-Biopsychosocial Questionnaire; BETY-BQ) in patients with ankylosing spondylitis (AS). Health Assessment Questionnaire for Spondyloarthropathies (HAQ-S), Ankylosing Spondylitis Quality of Life Questionnaire (ASQoL), Hospital Anxiety and Depression Scale (HADS), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), and Bath Ankylosing Spondylitis Functional Index (BASFI), were selected to investigate the validity of the BETY-BQ. Spearman's correlation coefficient was used as the data were not normally distributed. For scale reliability, the test-retest method was performed, Intraclass Correlation Coefficient (ICC) was calculated and Cronbach's alpha (α) coefficient was checked for internal consistency. The same scales were applied to patients under medical treatment at 3-month intervals for the determination of responsiveness. A total of 157 individuals took part, including 106 (67.5%) male participants and 51 (32.5%) female participants, with a mean age of 43.86±11.60 years. The correlations of BETY-BQ with the HAQ-S, ASQoL, HADS, BASDAI, and BASFI were very high to moderate (r = 0.819 to r = 0.583, p