Acute effects of air pollution on lupus nephritis in patients with systemic lupus erythematosus: A multicenter panel study in China

Air pollution may trigger systemic lupus erythematosus (SLE). However, few studies have investigated the associations between air pollution and complications of SLE, such as lupus nephritis (LN). In this study, multicenter longitudinal data from 13 hospitals in China, including 8552 SLE patients wit...

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Veröffentlicht in:	Environmental research 2021-04, Vol.195, p.110875, Article 110875
Hauptverfasser:	Bai, Heming, Jiang, Lei, Li, Ting, Liu, Chong, Zuo, Xiaoxia, Liu, Yi, Hu, Shaoxian, Sun, Linyun, Zhang, Miaojia, Lin, Jin, Xiao, Weiguo, Wang, Qingwen, Zhao, Dongbao, Wu, Huaxiang, Kong, Xiaodan, Gao, Wenkang, Hou, Wanxin, Seong, Myeongsu, Zhang, Yuanpeng, Chen, Fangfang, Chen, Sheng, Wu, Xin, Bao, Chunde, Wang, Li, Xu, Huji
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute effects Air Pollutants - analysis Air Pollutants - toxicity Air pollution Air Pollution - adverse effects Air Pollution - analysis China - epidemiology Environmental Exposure - analysis Humans Lupus Erythematosus, Systemic - epidemiology Lupus nephritis Lupus Nephritis - chemically induced Lupus Nephritis - epidemiology Nitrogen Dioxide - analysis Nitrogen Dioxide - toxicity Ozone - analysis Particulate Matter - analysis Particulate Matter - toxicity Sulfur Dioxide - analysis Systemic lupus erythematosus
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Zusammenfassung:	Air pollution may trigger systemic lupus erythematosus (SLE). However, few studies have investigated the associations between air pollution and complications of SLE, such as lupus nephritis (LN). In this study, multicenter longitudinal data from 13 hospitals in China, including 8552 SLE patients with 24,762 visits, were used. Based on the generalized estimating equation (GEE) model, we assessed the associations of LN occurrence with short-term exposures to different air pollutants including particulate matter with an aerodynamic diameter
ISSN:	0013-9351 1096-0953
DOI:	10.1016/j.envres.2021.110875