Design, synthesis and biological evaluation of a novel N-aminoacyl derivative of amphotericin B methyl ester as an antifungal agent

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Bibliographische Detailangaben
Veröffentlicht in:	European journal of medicinal chemistry 2021-02, Vol.211, p.113104, Article 113104
Hauptverfasser:	Zhang, Jinhua, Xu, Hongjiang, Dong, Yuanzhen, Chen, Minwei, Zhang, You, Shangguan, Wenwen, Zhao, Wenjie, Feng, Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	Amphotericin B Amphotericin B - analogs & derivatives Animals Antifungal activity Antifungal Agents - chemical synthesis Antifungal Agents - chemistry Antifungal Agents - pharmacokinetics Antifungal Agents - pharmacology Candida albicans - drug effects Drug Design Erythrocytes - drug effects Esters HEK293 Cells Hemolysis - drug effects Humans Hydrophilic oligomers Mice Mice, Inbred ICR Microbial Sensitivity Tests Molecular Structure Pharmacodynamics and pharmacokinetics Sheep Solid-phase synthesis
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