Quinolizinium-based tunable pH fluorescent probes for imaging in live cells

Quinolizinium-based tunable pH fluorescent probes for imaging in live cells

A new class of quinolizinium-based tunable pH fluorescent probes for cell imaging was developed. The probes showed turn “On” fluorescence response upon acidification brought by a modulation of photoinduced electron transfer (PET) from the N,N-dialkyl aniline substituent to the quinolizinium core ske...

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Veröffentlicht in:Dyes and pigments 2022-09, Vol.205, p.110541, Article 110541
Hauptverfasser: Sit, Hoi-Yi, Deng, Jie-Ren, Chan, Wing-Cheung, Ko, Ben Chi-Bun, Wong, Man-Kin
Format: Artikel
Sprache:eng
Schlagworte:
Cellular imaging
pH probe
Photo-induced electron transfer
Quinolizinium
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Zusammenfassung:A new class of quinolizinium-based tunable pH fluorescent probes for cell imaging was developed. The probes showed turn “On” fluorescence response upon acidification brought by a modulation of photoinduced electron transfer (PET) from the N,N-dialkyl aniline substituent to the quinolizinium core skeleton. These novel PET-based pH fluorescent probes displayed tunable emission properties in between 478 and 509 nm. Also, the probes exhibited tunable pH responsiveness with pKa ranging from
ISSN:0143-7208
1873-3743
DOI:10.1016/j.dyepig.2022.110541