Real-life experience with Dulaglutide: Analysis of clinical effectiveness to 24 months

Dulaglutide is an agonist of “glucagon-like peptide type 1″ receptors (arGLP1). The clinical efficacy of this molecule is based on reductions in glycosylated hemoglobin (HbA1c) and weight, data shown in the pivotal AWARD studies. We propose a retrospective and multicenter study that allows evaluatin...

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Veröffentlicht in:Diabetes research and clinical practice 2019-12, Vol.158, p.107916, Article 107916
Hauptverfasser: Moreno Obregón, Fernando, Miramontes-González, José Pablo, Romo Guajardo-Fajardo, Catalina, Nieto-Sánchez, Ángel, López-Suárez, José Manuel, Martín-Vallejo, Javier, Arco-Prados, Yolanda, Dolores García de Lucas, María, León-Jiménez, David
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Sprache:eng
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Zusammenfassung:Dulaglutide is an agonist of “glucagon-like peptide type 1″ receptors (arGLP1). The clinical efficacy of this molecule is based on reductions in glycosylated hemoglobin (HbA1c) and weight, data shown in the pivotal AWARD studies. We propose a retrospective and multicenter study that allows evaluating the effectiveness of dulaglutide at 24 months after treatment began, under conditions of usual clinical practice, and comparing the results obtained with those that are reflected in the controlled trials. The results show a reduction in the HbA1c levels −1.4% at 6 M and this reduction were maintained throughout 12 M and 24 M (p 
ISSN:0168-8227
1872-8227
DOI:10.1016/j.diabres.2019.107916