Clerodendrum viscosum Vent leaf extract supported nanosilver particles: Characterization, antiplasmodial and anticancer activity

[Display omitted] •Biosynthesis of Ag nanoparticles using water extract of Clerodendrum viscosum leaf.•Spherical shaped silver nanoparticles with an average diameter of 28.27 nm.•Exhibited excellent antiplasmodial activity against 3D7 strain of P. falciparum.•Demonstrated good anticancer activity against HeLa cells. Silver nanoparticles (AgNPs) were synthesized using water extract of Clerodendrum viscosum Vent leaf as reducing agent. The synthesized AgNPs were characterized by X-ray diffraction, UV–visible spectroscopy, X-ray photoelectron spectroscopy studies. Spherical shaped AgNPs were confirmed by FE-SEM and HRTEM analysis. NMR and FT-IR spectroscopy analysis suggested participation of biomolecules of C. viscosum extract for bioreduction and capping of AgNPs. These biosynthesize AgNPs exhibited significant antiplasmodial activity against 3D7 sensitive strain of Plasmodium falciparum with IC50 = 2.30 μg/ml. Further, AgNPs were investigated for anticancer property against human cervical cancer (HeLa) cell lines.