Taming glycosylidene carbenes through bench-stable glycosylidene diaziridines to access boro-ketosides

In this issue of Chem Catalysis, He and co-workers demonstrate easy access to diverse glycosyl boro-ketosides via a rare glycosylidene carbene intermediate. They use stable glycosylidene diaziridines as precursors for carbene generation, leading to products convertible into rare sugars and pharmaceutically interesting derivatives, such as tofogliflozin. In this issue of Chem Catalysis, He and co-workers demonstrate easy access to diverse glycosyl boro-ketosides via a rare glycosylidene carbene intermediate. They use stable glycosylidene diaziridines as precursors for carbene generation, leading to products convertible into rare sugars and pharmaceutically interesting derivatives, such as tofogliflozin.