Analysis of the bioactive components in Swietenia macrophylla leaves for their antibacterial and antioxidant capabilities
In this study, the extraction of bioactive compounds from Swietenia macrophylla leaves resulted in 50 % (v/v) acetone being the best solvent for extraction of gallic acid, total phenolic compounds, hydrolyzable tannins, and flavonoid content with maximum values of 58.769 μg/mL; 38.153 mgGAE/gdw; 10....
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Veröffentlicht in: | Bioresource technology reports 2023-06, Vol.22, p.101411, Article 101411 |
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Sprache: | eng |
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Zusammenfassung: | In this study, the extraction of bioactive compounds from Swietenia macrophylla leaves resulted in 50 % (v/v) acetone being the best solvent for extraction of gallic acid, total phenolic compounds, hydrolyzable tannins, and flavonoid content with maximum values of 58.769 μg/mL; 38.153 mgGAE/gdw; 10.586 mg/mL and 64.172 rutin/gdw respectively. FTIR studies indicated the presence of various compounds that have antimicrobial and antibacterial properties. Further, the study of antimicrobial activity showed that the sample acted against Gram-positive bacteria, but not Gram-negative bacteria. On conducting cyclic voltammetry and differential pulse voltammetry, CV showed an anodic peak at 0.2 V with a maximum peak current was at 212 μM; whereas DPV showed various anodic peak potentials at −0.05 V, 0.13 V, 0.23 V, and 0.65 V. TLC was used to qualitatively assess the presence of various bioactive compounds in the plant sample. This study produces bioactive chemicals that are antibacterial and antioxidant.
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•Extracted Bioactives from leaves of S. macrophylla and characterized.•The antioxidant property of extracts optimized using cyclic and DP voltammetry.•Antimicrobial activity of the Bioactives optimized at different concentrations.•First study on S. macrophylla leaves with antimicrobial and antioxidant effects |
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ISSN: | 2589-014X 2589-014X |
DOI: | 10.1016/j.biteb.2023.101411 |