Ketogenic diet improves and restores redox status and biochemical indices in monosodium glutamate-induced rat testicular toxicity
[Display omitted] This study investigated the effect of ketogenic diet on monosodium glutamate (MSG)-induced testicular dysfunction. Forty-six male rats (180 ± 40 g) were grouped into two groups (23 rats each); control group and MSG-induced group (4 mg/kg bw) for 28 days. At the 29th day, 5 rats fro...
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Veröffentlicht in: | Biomedicine & pharmacotherapy 2020-07, Vol.127, p.110227, Article 110227 |
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Format: | Artikel |
Sprache: | eng |
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This study investigated the effect of ketogenic diet on monosodium glutamate (MSG)-induced testicular dysfunction. Forty-six male rats (180 ± 40 g) were grouped into two groups (23 rats each); control group and MSG-induced group (4 mg/kg bw) for 28 days. At the 29th day, 5 rats from both group were sacrificed to establish testicular dysfunction. The remaining animals from the control group was further divided into three sub-groups and treated for 42 days; untreated group, ketogenic diet only and curcumin only as the standard drug (150 mg/kg bw). In the pre-treatment, the administration of MSG resulted in a significant (p |
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ISSN: | 0753-3322 1950-6007 |
DOI: | 10.1016/j.biopha.2020.110227 |