Turmeric Kombucha as effective immunomodulator in Salmonella typhi-infected experimental animals

This study investigated the immunomodulatory effects of turmeric and black tea kombucha in the experimental animal. The kombucha was administrated orally to non-infected as well as Salmonella typhi-infected Balb-C mice and samples were taken to study the in vivo immunomodulatory activity of the kombucha. Both turmeric and black tea kombucha enhanced the adaptive immune response (indicated by an increase in CD4+, TNFα, IFN-γ) and innate immune response (evidenced by a decrease of CD68 IL-6). Although both samples showed notable positive results, the in vivo immunomodulatory activity of turmeric kombucha was much pronounced compared to black tea kombucha. •This study investigated the immunomodulatory effects of turmeric in the experimental animal.•Turmeric kombucha enhance the adaptive immune response and innate immune response.•Immunomodulatory activity of turmeric kombucha was much pronounced compared to black tea kombucha.